tolbutamide

IPA: tˈoʊɫbjutʌmaɪd

Examples of "tolbutamide" in Sentences

Type 2 diabetes that went through a strikingly similar controversy: tolbutamide.
Data presented indicated that tolbutamide increased cardiovascular deaths by over two and a half times.
Inform patient that alcohol may react with tolbutamide and cause Antabuse - like reaction (eg, flushing, headache, dizziness, high BP).
The headline appeared almost exactly 35 years ago, on July 4, 1975, about a different drug for Type 2 diabetes that went through a strikingly similar controversy: tolbutamide.
Clinically meaningful interactions would not be expected with other sulfonylureas (e.g., glipizide, tolbutamide, and glimepiride) which, like glyburide, are primarily eliminated by CYP2C9.
Kangkong showed oral hypoglycaemic activity in tests with diabetic humans and rats; it was shown that an aqueous leaf extract can be as effective as tolbutamide in reducing blood glucose levels
Metformin and sulfonylurea drugs -- the latter a class of diabetes drugs including glyburide, glipizide, chlorpropamide, tolbutamide and tolazamide -- are often among the first medications prescribed to lower blood sugar levels in people with type 2 diabetes.
In time, the reputation of the class of diabetic drugs to which tolbutamide belonged was salvaged to some degree by proposing that tolbutamide might interfere with a purported pathophysiologic mechanism called "ischemic preconditioning" while others drugs in this family might not.