noun

• Any of several trees of the genus Nyssa which grow in swampy regions on the eastern, southern and midwestern United States.
• (in particular) Nyssa aquatica.
• (in particular) Nyssa multiflora, a North American tree of the dogwood family, with brilliant, glossy foliage and acid red berries.
• A city in and the county seat of Lee County, Mississippi, United States.
• A town in Jackson County, Arkansas, United States.
• A city in Coal County, Oklahoma, United States.