zidovudine
IPA: zˈɪdˈoʊvʌdaɪn
noun
- (pharmacology) A nucleoside analog reverse-transcriptase inhibitor C₁₀H₁₃N₅O₄, a type of antiretroviral drug that inhibits replication of some retroviruses (such as HIV) and was first approved for the treatment of AIDS.
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Examples of "zidovudine" in Sentences
- These findings were largely unaffected by zidovudine use.
- Treatment options that have been tried include zidovudine and the CHOP regimen.
- Combivir made by Britain's GlaxoSmithKline PLC contains lamivudine and zidovudine.
- Both groups also took a short course of a fourth drug, zidovudine, better known as AZT.
- AZT is "toxic" … year … nobody calls zidovudine "AZT" since 1980s, except for AIDS-dissidents.
- Like the earliest anti-HIV drugs such as zidovudine (AZT), introduced 10 years earlier, these block enzymes vital for viral multiplication.
- Expectant mothers were also treated with a cocktail of zidovudine and didanosine from week 36 of their pregnancies until one week after delivery.
- Among the new discounts announced Monday is a $66-a-year price for a combination treatment for children based on zidovudine, a staple of AIDS treatment.
- The WHO recommended "that countries progressively phase out the use of stavudine as a preferred first-line therapy option and move to less toxic alternatives such as zidovudine
- Therefore countries should progressively phase out the use of stavudine as a preferred first-line therapy option and move to less toxic alternatives such as zidovudine (AZT) or tenofovir (TDF), WHO recommended.
- Treatment options include a one-month course of zidovudine (AZT) during the last weeks of pregnancy or a single dose of nevirapine during delivery followed by a single dose to the infant within 72 hours of birth.
- Some countries - notably South Africa - are loath to buy or distribute low-cost drugs, such as zidovudine and nevirapine, that have been shown to slash the risk of mother-to-child transmission through birth or breast-feeding by up to two-thirds.