cinchonine
IPA: sˈɪntʃɔnaɪn
noun
- (organic chemistry) An alkaloid, obtained from the bark of cinchona trees, that is used as an antimalarial agent.
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Examples of "cinchonine" in Sentences
- It is stated that incomplete examinations have detected _cinchonine_ in the bark.
- Dr. Farr detected a considerable amount of cinchonine in it, but was prevented from completing his examination.
- When cinchonine is distilled with solid potassium hydrate, it yields pyrrol and bases of both the pyridine and quinoline series.
- _Cinchonidine_, when heated with potassium hydrate, yields quinoline also, and with nitric acid the same products as cinchonine.
- When cinchonine is treated with potassium hydrate, it is decomposed into quinoline and a solid body, which on further treatment yields a liquid base,
- The true cinchona barks, containing quinine, quinidine, and cinchonine, are distinguished from the false by their splintery-fibrous texture, the latter being pre-eminently corky.
- Their great value depends upon the presence of certain alkaloid substances called quinine, cinchonine, and quinidine, which exist in the bark in combination with tannic and other acids.
- The gray bark of Huanuco is derived from _Cinchona micrantha_, which is characterized by its yield of cinchonine, and the Loxa or Loja barks are furnished in part by _Cinchona officinalis_, and are especially rich in quinidine.
- ~ -- Picric acid forms insoluble salts with many of the alkaloids, and picric acid may be determined in the following manner: -- To the solution of picric acid, or a picrate, add a solution of sulphate of cinchonine acidulated with H_ {2} SO_ {4}.
- For example, cinchonine and quinine both afford the basic quinoline under certain conditions, but on oxidation of cinchonine, an acid -- cinchoninic acid (C_ {10} H_ {7} NO_ {2}) -- is the principal body formed, while in the case of quinine, quininic acid (C_ {10} H_ {9} NO_ {3}) is the principal product.
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