cofactor
IPA: kˈoʊfæktɝ
noun
- A contributing factor.
- (biochemistry) A substance, especially a coenzyme or a metal, that must be present for an enzyme to function.
- (biochemistry) A molecule that binds to and regulates the activity of a protein.
- (mathematics) The result of a number being divided by one of its factors.
- (mathematics, linear algebra, of a matrix) The signed determinant of the submatrix produced by removing the row and column containing a specified element; primarily used in the recursive definition and calculation of the determinant of a matrix.
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Examples of "cofactor" in Sentences
- It has one cofactor the flavin FAD.
- It requires potassium as a cofactor.
- Manganese is required as a cofactor.
- A magnesium ion is involved as a cofactor.
- Heme is a cofactor of the protein hemoglobin.
- Trivalent chromium is the cofactor of insulin.
- The adjoint is the Transpose of the Cofactor matrix.
- It makes no mention of the requirement of a cofactor.
- F2RL2 is a cofactor for F2RL3 activation by thrombin.
- A portion of the heparin forms a complex with the cofactor.
- PQQ is a substance that was discovered in 1979 as a cofactor in bacterial enzyme activity.
- Enzymatic methane production involves the tiny molecule deazaflavin, known as cofactor F0 or cofactor F420.
- The broad array of lysosomal storage diseases and peroxisomal disorders are presented along with the defects in transport, vitamin cofactor and metal metabolism.
- "It took several years, but at last we were able to recreate in the test tube what happens inside mycobacterial cells when the bacterial enzyme, which we named Ddn, and a second bacterial component called a cofactor, interact with PA-824," says Dr. Barry.
- The thyroid uses glutathione, a combination of three amino acids (glycine, glutamine, and cysteine), protectively as an antioxidant or free radical quencher and as a cofactor that makes it possible for one of its most important enzymes (5'-deiodinase) to work (6).
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