fluvastatin
IPA: fɫˈuvˈæstʌtɪn
noun
- (pharmacology) A drug of the statin class, used to treat hypercholesterolemia and to prevent cardiovascular disease.
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Examples of "fluvastatin" in Sentences
- Overall effects of fluvastatin were similar to those of statins in other populations.
- After a mean follow-up of 5.1 years, fluvastatin lowered LDL cholesterol concentrations by 32%.
- Although cardiac deaths and non-fatal MI seemed to be reduced, fluvastatin did not generally reduce rates of coronary intervention procedures or mortality.
- Patients who were initially randomized to fluvastatin or placebo in the 5 - to 6-year trial were offered open-label fluvastatin in a 2-year extension of the original study.
- A study from Japan using a cell culture assay system reported that inteferon plus fluvastatin inhibited hepatitis C virus more effectively than did inteferon plus ribaviran.
- Previous data suggest that lipophilic statins such as fluvastatin and N-bisphosphonates such as zoledronic acid, both inhibitors of the mevalonate metabolic pathway, have anti-cancer effects in vitro and in patients.
- Risk reduction with fluvastatin for the primary endpoint [a heart attack, fatal or nonfatal - ss] ... was not significant, although there were fewer cardiac deaths or non-fatal MI ... in the fluvastatin group than in the placebo group.
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