imidazole
IPA: ˈɪmʌdʌzˈoʊɫi
noun
- (organic chemistry) A heterocyclic organic compound containing two nitrogen atoms separated by a carbon atom in a five-membered ring, called 1,3-diazole in IUPAC nomenclature.
- (organic chemistry) A group of compounds containing that structure.
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Examples of "imidazole" in Sentences
- First there are the imidazole derivatives.
- Bifonazole is an imidazole antifungal drug.
- It is another member of the nitro imidazole family.
- Imidazolidine is the hydrogen saturated of imidazole.
- Imidazole is a heterocyclic aromatic organic compound.
- Imidazole is an organic compound with the formula C3H4N2.
- Butoconazole is an imidazole antifungal used in gynecology.
- Nafimidone is an anticonvulsant drug of the imidazole class.
- Propenidazole is an imidazole derivative used in gynecology.
- Imidazolidine is the hydrogen saturated analogue of imidazole.
- Free imidazole compounds in white and dark muscles of migratory marine fish.
- Another rich field of investigation from biological viewpoint was that of imidazole derivatives.
- The experimental drug, BW - 322, the imidazole derivative of 6-MP, seemed to have the best therapeutic index.
- It was also his interest in the imidazole derivatives that prompted him to examine the structure of the antineuritic vitamin.
- Bound proteins were eluted by adding 100 µL of Tris-Cl pH 8.0, 300 mM NaCl, 250 mM imidazole and collecting the flow through.
- The dark blue copper ion is bonded in a cavity between two imidazole groups (the five-membered rings) and two yellow sulphur atoms.
- Remaining unbound proteins were removed by washing the nickel resin 4X with 200 µL of 50 mM Tris-Cl pH 8.0, 300 mM NaCl, and 50 mM imidazole.
- This in turn led to his demonstration that histidine, a building-stone of proteins, is an imidazole alanine, and to his discovery of histamine
- The production of imidazole derivatives as a result of this reaction induced him to demonstrate the presence of a prototype of the imidazole ring in proteins.
- Cooperating with the I.G. Farbenindustry, which supplied the precious raw material for the work, he was able to prove that not an imidazole-ring (as suggested by Jansen and Donath), but a thiazole - and a pyrimidine-ring are present in vitamin