imidazole

IPA: ˈɪmʌdʌzˈoʊɫi

(organic chemistry) A heterocyclic organic compound containing two nitrogen atoms separated by a carbon atom in a five-membered ring, called 1,3-diazole in IUPAC nomenclature.
(organic chemistry) A group of compounds containing that structure.

Examples of "imidazole" in Sentences

Free imidazole compounds in white and dark muscles of migratory marine fish.
Another rich field of investigation from biological viewpoint was that of imidazole derivatives.
The experimental drug, BW - 322, the imidazole derivative of 6-MP, seemed to have the best therapeutic index.
It was also his interest in the imidazole derivatives that prompted him to examine the structure of the antineuritic vitamin.
Bound proteins were eluted by adding 100 µL of Tris-Cl pH 8.0, 300 mM NaCl, 250 mM imidazole and collecting the flow through.
The dark blue copper ion is bonded in a cavity between two imidazole groups (the five-membered rings) and two yellow sulphur atoms.
Remaining unbound proteins were removed by washing the nickel resin 4X with 200 µL of 50 mM Tris-Cl pH 8.0, 300 mM NaCl, and 50 mM imidazole.
This in turn led to his demonstration that histidine, a building-stone of proteins, is an imidazole alanine, and to his discovery of histamine
The production of imidazole derivatives as a result of this reaction induced him to demonstrate the presence of a prototype of the imidazole ring in proteins.
Cooperating with the I.G. Farbenindustry, which supplied the precious raw material for the work, he was able to prove that not an imidazole-ring (as suggested by Jansen and Donath), but a thiazole - and a pyrimidine-ring are present in vitamin