imipramine
IPA: ˈɪmɪprʌmaɪn
noun
- (pharmacology) A synthetic compound (trademark Tofranil) used to treat depression.
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Examples of "imipramine" in Sentences
- Desipramine is an active metabolite of imipramine.
- Clomipramine is the 3 chlorinated derivative of imipramine.
- The study focused on Paxil from GlaxoSmithKline and imipramine.
- Effects of imipramine on circadian rhythms in the golden hamster.
- This compound has a different three ring structure from imipramine.
- This compound has a different three ring structure than imipramine.
- TCAs include imipramine, amitriptyline, desipramine and nortriptyline.
- And in comparison with a shiny imipramine molecule he wins hands down.
- This “vital disturbance,” Kuhn claimed, is what imipramine was uniquely suited to treat.
- Finally, he experienced some relief when he switched to an old-fashioned tricyclic antidepressant called imipramine.
- Amphetamines only made you feel better, but imipramine made you feel well—which meant that you must have been sick all along.
- The other showed that an antidepressant called imipramine, which was known to block NPC1, seemed to prevent infection as well.
- Endogenous depression was exactly the disease that imipramine cured, and the proof that you had been sick was that imipramine cured you.
- Enhancement of brain dopamine activity has been implicated in Imipramine's ability to stimulate motor activity and prolong time spent in escape in mice.
- His data was overwhelming, his enthusiasm even stronger, but G22355—by then known as imipramine—was hardly taking the world by storm, and Kuhn was roundly ignored.
- And when Axelrod showed that imipramine worked the latter way, blocking the reuptake of norepinephrine, it was easy to believe that the catecholamine hypothesis was correct.
- The studies showed that this was true, whether or not the patients took Paxil, a selective serotonin reuptake inhibitor (SSRI), or imipramine, a tricylcic, an older generation of anti-depressant medication.
- At a time when psychoanalysis was the mainstay of psychiatry, he was arguing that imipramine could “bring a complete change in the situation within a few days, which could not be achieved by intensive prolonged psychotherapy.”
- A class of older antidepressants called tricyclics, such as amitriptyline (Elavil) or imipramine (Tofranil), are effective at staving off chronic tension-type headaches in many people who have not found relief with over-the-counter medications.