kinetochore

IPA: kɪnˈɛtʌkɔr

(biology) The protein structure in eukaryotes which assembles on the centromere and links the chromosome to microtubule polymers from the mitotic spindle during mitosis.

Examples of "kinetochore" in Sentences

During meiosis, fibres called microtubules attach themselves to the centre kinetochore of the chromosomes.
These complexes become attached to some of the spindle microtubules, which are then termed kinetochore microtubules.
The kinetochore protein Mtw1 was epitope-tagged, allowing us to score the number of kinetochore foci in spread nuclei.
We now believe that proteins in a structure called the kinetochore are among the most sensitive to degradation or mutation.
Spindle fibers, composed of microtubules, have attached to the sister pairs of chromosomes at their point of attachment the kinetochore, or centromere.
This force increases the efficiency with which chromosomes make bipolar spindle attachments and regulates kinetochore activities necessary for chromosome oscillation, but is not essential for chromosome congression.
The initial study of centromere coupling reported that in chromosome spreads exhibiting centromere coupling, Zip1 foci and kinetochore pairs occur in approximately equal numbers (about sixteen) and exhibit a high level of co-localization
Overlaid onto these signals that promote orchestrated cell division are checkpoints that ensure appropriate mitotic spindle formation, a lack of DNA damage, kinetochore attachment, and that each daughter cell has the appropriate complement of DNA.