norethindrone
IPA: nˈɔrθɪndrˈoʊn
noun
- (pharmacology) US form of norethisterone. [(pharmacology) A synthetic steroid hormone, 19-nor-17α-ethynyltestosterone (C₂₀H₂₆O₂), which has actions similar to those of progesterone and is used chiefly for contraception.]
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Examples of "norethindrone" in Sentences
- (Chemically, norethindrone is 17a-ethinyl-19-nortestosterone; its generic name in Europe is norethisterone).
- She also tries different hormones, such as norethindrone, a type of progesterone more commonly used in Europe.
- Even today, norethindrone, though not norethynodrel, is still used by millions of women as an oral contraceptive.
- Some women find that taking an oral contraceptive that contains the older progestin called norethindrone at a dose of 1.5 nanograms helps restore the proper balance for libido.
- Mexican pharmaceutical company, Syntex, S.A., first synthesized an orally active progestational steroid, named norethindrone, which does not exist in nature and that they supplied Pincus with this steroid for further biological work.
- One and one-half years after the first publication by the Syntex group, chemists at G.D. Searle -- a company for which Pincus consulted, synthesized a close relative, norethynodrel, which, as shown by Pincus -- is largely converted in the stomach into norethindrone.
- None of Pincus's and Rock's work would have been possible without the initial chemical breakthrough in Mexico on deliberately synthesizing an orally effective progestin -- an achievement which was recognized by the National Medal of Science in 1973 in the White House and in 1978 by inclusion of Syntex's norethindrone as the first ever drug in the
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