nuclease

IPA: nukɫiˈeɪz

(biochemistry) Any of several enzymes capable of cleaving the phosphodiester bonds between the nucleotide subunits of nucleic acids.

Examples of "nuclease" in Sentences

An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells.
F.A. Cotton, which has determined the three-dimensional structure of nuclease at high resolution.
The enzyme, which they named FAN1, appears to be a nuclease, which is capable of slicing through strands of DNA.
Each finger binds to a specific combination of DNA bases and is attached to a DNA-cutting enzyme called a nuclease.
It was also demonstrated that a ribonuclease III-like nuclease, called Dicer, is responsible for the processing of dsRNA to short RNA34.
Support for a particulate substructure of chromatin came from electron microscopy and from nuclease digestion and sedimentation analysis.
The micrococcal nuclease calcium dependence was put to good use by Hugh Pelham, a graduate student in the lab, who developed the use of nuclease treatment of the lysate to assay heterologous mRNAs.
One other thing I learned about during the studies on the inhibition of protein synthesis by dsRNA was that micrococcal nuclease, which requires Ca2+ for activity, did not inhibit protein synthesis in the reticulocyte lysate provided no Ca2+ was present.