nuke

IPA: nˈuk

A nuclear weapon.
(by extension) Something that destroys or negates, especially on a catastrophic scale.
A nuclear power station.
(nautical) A vessel such as a ship or submarine running on nuclear power.
A person (such as a sailor in a navy or a scientist) who works with nuclear weapons or nuclear power.
(warez) A cautionary flag placed on a release to label it as "bad" for some reason or another (e.g., being a dupe of a previous release or containing malware).
(rare) A microwave oven.
Alternative spelling of nuc (“nucleus colony of bees”) [(beekeeping) A nucleus colony; a small bee colony created from a larger colony.]
(anatomy, obsolete) Alternative form of nucha (“spinal cord; nape of the neck”) [(anatomy, obsolete) The spinal cord.]
(chiefly Northern England, archaic) Alternative form of nook (“a corner of a piece of land; an angled piece of land, especially one extending into other land”) [A small corner formed by two walls; an alcove.]

(transitive, chiefly US, colloquial) To use a nuclear weapon on a target.
(transitive, chiefly US, colloquial, figuratively) To destroy or erase completely.
(transitive, Internet slang, by extension) To carry out a denial-of-service attack against (an IRC user).
(transitive, chiefly US, colloquial) To expose to some form of radiation.
(transitive, chiefly US, colloquial) To cook in a microwave oven.
(transitive, warez) To flag a release as bad for some reason or another (for instance, due to being a duplicate of an earlier release or containing malware).
(transitive, US, nautical, colloquial) To overanalyze or despair unduly over something.

Examples of "nuke" in Sentences