spironolactone
IPA: spɝˈɑnoʊɫˈæktoʊn
noun
- (pharmacology) A steroid drug which acts as an antimineralocorticoid (for which purpose it is used in the treatment of certain types of edema and hypertension) and an antiandrogen (for which purpose it is used as part of some types of hormone therapy, especially for transgender women).
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Examples of "spironolactone" in Sentences
- I doubt this problem could happen with spironolactone.
- Spironolactone is probably the most commonly used drug in the US.
- Some birth control pills and spironolactone reduce androgen levels.
- The risk is high in concurrent use of ACE inhibitors or spironolactone.
- These lactones are valuable intermediates in the synthesis of spironolactone.
- That leaves spironolactone as perhaps the only option for lowering testosterone after cancer.
- For acne or excess hair growth, a water pill (diuretic) called spironolactone may be prescribed to help reverse these problems.
- Antiandrogen treatment with drugs such as spironolactone and flutamide is effective in some patients, but is not approved by the FDA for the treatment of hair loss.
- A doctor may prescribe a low-dose antibiotic or a medication called spironolactone or Aldactone, which has antitestosterone properties that reduce oil production in the skin.
- An old drug called spironolactone and a newer one called eplerenone can lower mortality for patients with severe heart failure, but they can also cause dangerous elevations in potassium levels.
- While female-pattern hair loss caused by a hormonal imbalance can be treated with prescription medications such as spironolactone or oral contraceptives, it is important that women see their dermatologist for proper diagnosis and treatment.
- A government-funded study is testing whether spironolactone, which is a type of drug known as an aldosterone antagonist, can reduce the death rate among these patients; the trial is expected to be completed in about 2012. peter. loftus@dowjones.com
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