noun

• (US) Any of several North American plane trees, of the genus Platanus, especially Platanus occidentalis (American sycamore), distinguished by its mottled bark which flakes off in large irregular masses.
• (Britain) A large British and European species of maple, Acer pseudoplatanus, known in North America as the sycamore maple.
• (originally) A large tree bearing edible fruit, Ficus sycomorus, allied to the common fig, found in Egypt and Syria.
• A number of places in the United States:
• An unincorporated community in Talladega County, Alabama.
• An unincorporated community in Colusa County, California.
• Former name of Herndon, California.
• An unincorporated community in Sussex County, Delaware.
• A minor city in Turner County, Georgia.
• A city, the county seat of DeKalb County, Illinois.
• An unincorporated community in Jackson Township, Howard County, Indiana.
• An unincorporated community in Montgomery County, Kansas.
• A minor city in Jefferson County, Kentucky.
• An unincorporated community in Ozark County, Missouri.
• A village in Wyandot County, Ohio.
• A census-designated place in Delaware County, Oklahoma.
• A census-designated place in Sequoyah County, Oklahoma.
• A town in Allendale County, South Carolina.
• An unincorporated community in Calhoun County, West Virginia.
• An unincorporated community in Logan County, West Virginia.
• A number of townships in the United States, listed under Sycamore Township.