translocation

IPA: trænsɫoʊkˈeɪʃʌn

noun

  • Removal of things from one place to another; displacement; substitution of one thing for another.
  • (genetics) A transfer of a chromosomal segment to a new position, especially on a nonhomologous chromosome; the segment so transferred.
  • (biochemistry) A transfer of a molecule through a membrane.
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Examples of "translocation" in Sentences

  • Twin arginine translocation pathway.
  • Mechanisms of membrane translocation.
  • Retro translocation into the cytosol.
  • The translocation has not occurred yet.
  • Anthrax toxin assembly and translocation.
  • They are a type of chromosomal translocation.
  • This translocation is not a mere marker of APL.
  • The failure of p65 translocation to the nucleus . . .
  • A person with such a translocation is phenotypically normal.
  • Present view of protein translocation across the ER membrane.
  • This genetic event was termed a translocation—the flip-flop transposition of two pieces of chromosomes.
  • The rearranged genetic region, called a translocation, leads to the production of a fusion gene and an abnormal protein and, ultimately, to leukemia.
  • Just over half, 51%, had one or more cancer gene mutations or an abnormality called a translocation, in which a section of DNA gets incorporated into the wrong chromosome.
  • These forms of leukemia share a common molecular abnormality called a translocation in which a gene on chromosome 11 breaks and becomes joined with one of many genes on different chromosomes.
  • Beginning in 1972, she made a number of remarkable discoveries, including the landmark finding that an abnormally short chromosome associated with chronic myelogenous leukemia (CML) was not a chromosome deletion, as many scientists had thought, but an exchange (known as a translocation) of segments between two chromosomes.

Related Links

synonyms for translocationdescribing words for translocation
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