trypsinogen
IPA: trˈɪpsʌnʌdʒʌn
noun
- (biochemistry) An inactive precursor of trypsin
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Examples of "trypsinogen" in Sentences
- Serum trypsinogen is measured using a blood test.
- As a result, the zymogen trypsinogen breaks down into trypsin.
- Once activated, the trypsin can activate more trypsinogen into trypsin.
- Trypsin is produced in the pancreas as the inactive proenzyme trypsinogen.
- Evolution of antifreeze glycoprotein gene from a trypsinogen gene in Antarctic notothenioid fish.
- The intact gland contains an inactive precursor trypsinogen, which is converted into the protein-dissolving enzyme trypsin only by contact with duodenal juice.
- Cheng, in 1998, described the evolution of diverse antifreeze proteins in Antarctic fish, one of which was co-opted from a digestive enzyme called trypsinogen.
- Chen et al. demonstrate that an Antifreeze Glycoprotein AFGP gene from the Antarctic notothenioid Dissostichus mawsoni derives from a gene encoding a pancreatic trypsinogen.
- The trypsinogen system was investigated (with Bode) in great detail by low temperature crystallography, gamma-ray spectroscopy, chemical modification, and molecular dynamics calculations.
- I found this interesting , not only because of the evolutionary implications, but also because protease zymogens like trypsinogen act as autocatalytic systems in organisms like me and you, Sal: Trypsinogen enters the small intestine, and gets a peptide bond cloven and breaks down into trypsin.
- A remarkable twist to this conventional gene-duplication/sequence-divergence paradigm is the creation of a unique functional antifreeze glycoprotein (AFGP) sequence from partly non-coding DNA in Antarctic notothenioid fish, involving de novo duplications of a 9-nt sequence spanning an exon-intron junction of an ancestral trypsinogen-type protease gene to form a large, highly repetitive (ThrAlaAla)n coding region, and shedding most of the protease gene structure.
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